All Clinical Trials
Search our team at AdventHealth Research Institute
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NCT06745284
An active-comparator-controlled, open-label, parallel group study to evaluate the effect of survodutide on energy expenditure and fatty acid oxidation in subjects with obesity
This study is currently enrolling.Research Area: Translational Research -
NCT05675410
A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
This study is currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe overall goal of this study is to compare the effects, good and/or bad, of brentuximab vedotin and nivolumab (Bv-NIVO) against standard therapy for people with HL to find out which is better.
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NCT04066348
Clinical Trial of Etanercept (TNF-a Blocker) for Treatment of Blast-Induced Tinnitus
This study is currently enrolling.Research Area: Digestive Health and Surgery -
NCT06707688
Pre-market IDE study of the Amulet™ 2 LAA Occluder VERITAS Study
This study is currently enrolling.Associated Conditions: ElectrophysiologyResearch Area: Heart, Lung and Vascular ResearchThe purpose of this research study is to see how well the experimental Amulet 2 device works and how well tolerated it is. The Amulet 2 device is used in patients with an irregular heartbeat that is...
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NCT05637801
A Randomized, Double-blind, Sham-controlled, Adaptive- Design Pivotal Study of Sensory Stimulation in Subjects with Alzheimer’s Disease
This study is currently enrolling.Associated Conditions: NeurodegenerativeResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaIn this study, researchers want to find out if sensory stimulation delivered using the Sensory Stimulation System may help slow disease progression in people with mild to moderate Alzheimer’s disease...
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NCT05514717
A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of XMT-2056 in Participants with Advanced/Recurrent Solid Tumors that Express HER2
This study is currently enrolling.Associated Conditions: Metastatic Solid TumorsResearch Area: Clinical Cancer ResearchResearch Location: Celebration, FloridaThe purpose of the study is to: During the Dose Escalation part, find the most tolerated dose of the Study Drug that may provide potential benefit. During the Enrichment and Expansion parts, further...
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NCT06667076
A Phase 2, Open-Label, Multi-cohort Study of Subcutaneous Amivantamab in Combination with Lazertinib as First-Line Treatment, or Subcutaneous Amivantamab in Combination with Platinum-based Chemo as Second-line Treatment, in Participants with EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
This study is currently enrolling.Associated Conditions: Lung CancerResearch Area: Clinical Cancer Research -
NCT05611931
A Phase 3, Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial of Selinexor in Maintenance Therapy After Systemic Therapy for Patients With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
This study is currently enrolling.Associated Conditions: Endometrial CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this Phase 3 study is to compare the PFS of patients receiving Selinexor maintenance therapy after prior systemic therapy to the PFS of patients receiving placebo as maintenance therapy...
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NCT06172296
A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma
This study is currently enrolling.Associated Conditions: NeuroblastomaResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe overall goals of this study are to
Compare the outcomes of dinutuximab given early with Induction therapy to the effects of standard Induction therapy with the addition of dinutuximab later in... -
NCT06619561
A Phase 2, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, PK, and Efficacy of Vimseltinib in Adults With Active Chronic GVHD After Failure of Prior Systemic Therapy
This study is currently enrolling.Research Area: Clinical Cancer Research -
NCT05812807
OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy
This study is currently enrolling.Associated Conditions: Breast CancerResearch Area: Clinical Cancer ResearchThis study is being done to answer the following question: Among patients with early-stage TNBC who achieve a pCR after preoperative chemotherapy in combination with pembrolizumab, will observation...
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NCT06993454
ACELERATE-P: Acute exercise and endogenous glucose production in type 2 diabetes: Implications for glycemic control and treatment of hepatic steatosis
This study is currently enrolling.Research Area: Translational Research