Clinical Trials
Search our team at AdventHealth Research Institute
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NCT00097292
TRIALNET: Natural History Study of the Development of Type 1 Diabetes
This study is currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaYou are being asked to be in a research study called the TrialNet Natural History Study of the Development of Type 1 Diabetes. As you know, TrialNet is an international research group dedicated to the...
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NCT02402244
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaWe are doing this study to find better ways to diagnose, treat and prevent cancers in children, adolescents and young adults. To do this, we need to learn more about cancers that happen to children...
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NCT01515787
A Phase II/III of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision (PROSPECT)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, Florida[$] [Abbreviated - Closed] The purpose of this study is to compare the effects, both good and bad, of the standard treatment of chemotherapy and radiation to chemotherapy using a combination regimen...
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NCT03334292
Natural History of Wilson Disease: Registry for Patients with Wilson Disease
This study is currently enrolling.Associated Conditions: Wilson’s DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaYou are invited to donate your blood, urine, research data, and related information to be stored (banked) in a research specimen/data database or bank where it can be used for future research projects...
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North American Pediatric Renal Trials Collaborative Studies (NAPRTCS)
This study is currently enrolling.Associated Conditions: TransplantResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaNAPRTCS is a research effort that was organized in 1987 by a group of physicians and surgeons committed to the success of pediatric renal transplant.
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NCT06819007
A Phase 3, Open-label, Multicenter, Randomized Trial of Trastuzumab Deruxtecan with Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Therapy in HER2-Expressing Ovarian Cancer” GOG 3112/ DSI-T-DXd ENHERTU (DO-01); DESTINY-Ovarian01 (DO-01)] DS8201-772
This study is not currently enrolling.Associated Conditions: Ovarian, Fallopian, or Primary Peritoneum CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis study consists of two parts: Part 1 (safety run-in) and Part 2 (randomized part [like the flip of a coin]). The purpose of Part 1 is to learn more about the safety and tolerability of the...
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NCT06676072
Safety and effectiveness of the TactiFlex SE Catheter and Volt Pulsed Field Ablation (PFA) Generator in subjects with paroxysmal atrial fibrillation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of the study is to find out if the investigational TactiFlex PFA System, the device that is being studied, is safe and effective in treating adults like you who have atrial fibrillation
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NCT05463731
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline
This study is not currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThis study is looking to assess the effect of remternetug versus
placebo on time to clinically meaningful
progression in participants with early AD. -
NCT06579105
SOLSTICE: A Phase IIb, Randomized, Double-blind, Placebo-controlled and Open-label Active Comparator Study to Evaluate the Efficacy, Safety, and Tolerability of AZD5004 in Adults with Type 2 Diabetes Mellitus
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: The purpose of this study is to evaluate if the study medication AZD5004 can help improve glycemic control in persons with type 2 diabetes in conjunction with diet and exercise as...
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NCT06131372
NN9388-7700: Efficacy and safety of co-administered cagrilintide s.c. 2.4 mg in combination with semaglutide s.c. 2.4 mg (cagrisema s.c. 2.4 mg/2.4 mg) once-weekly compared to semaglutide, cagrilinitide and placebo in people with chronic kidney disease and type 2 diabetes.
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: The purpose of this study is to see whether CagriSema can lower kidney damage. This will be compared to the effects of semaglutide, cagrilintide and placebo.
Study Duration...
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NCT05845710
Protection against Emboli during caRotid artery stenting using a Neuroguard IEP® Direct 3-in-1 delivery system comprised oF a pOstdilation balloon, integRated eMbolic filter, and A Novel Carotid stEnt III
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaTo evaluate the safety and effectiveness of direct carotid access for stenting using
the Neuroguard IEP Direct System in subjects at high risk for carotid
endarterectomy who require carotid... -
NCT06081894
A PHASE 3, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF AFICAMTEN COMPARED TO PLACEBO IN ADULTS WITH SYMPTOMATIC NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY Department #: 407-303-7556
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of this study is to compare the effects of aficamten and placebo on health status and exercise capacity in participants with nHCM. The safety and tolerability of aficamten at different...