All Clinical Trials
Search our team at AdventHealth Research Institute
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NCT03142152
Assessment of the Carillon Mitral Contour System® in Treating Heart Failure with Functional Mitral Regurgitation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Tampa, FloridaThe purpose of this clinical study is to evaluate the safety and effectiveness of the Carillon Mitral Contour System in people who have mitral regurgitation resulting from heart failure.
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NCT06616974
A Phase 2, Double-blind, Randomized, Placebo-Controlled Study to Assess the Efficacy and Safety of TX000045 After 24 Weeks of Treatment in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (PH-HFpEF)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchThe study Sponsor is developing the investigational (experimental) drug TX000045 as a potential new treatment for patients with high lung blood pressure due to heart failure.
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Discovery and Characterization of Genetic Risk Loci in Sjögren’s Syndrome
This study is not currently enrolling.Research Area: Pediatric Research and Clinical Trials -
NCT06676072
Safety and effectiveness of the TactiFlex SE Catheter and Volt Pulsed Field Ablation (PFA) Generator in subjects with paroxysmal atrial fibrillation
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of the study is to find out if the investigational TactiFlex PFA System, the device that is being studied, is safe and effective in treating adults like you who have atrial fibrillation
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NCT05463731
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline
This study is not currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThis study is looking to assess the effect of remternetug versus
placebo on time to clinically meaningful
progression in participants with early AD. -
NCT06400342
The REVIVE-TAVR (Randomized Evaluation of Valve-In-Valve versus Explantation for failed Transcatheter Aortic Valve Replacement)
This study is not currently enrolling.Research Area: Heart, Lung and Vascular Research -
Retrospective Data Collection of Ultrasound Media from Subjects Implanted with Impella® Device
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Tampa, Florida -
NCT06456463
A Phase II multicenter open-label trial of tagraxofusp (Tag) in combination with venetoclax and azacitidine (Ven/Aza) in adults with previously untreated CD123+ acute myeloid leukemia (AML) who are ineligible for intensive chemotherapy.
This study is not currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer Research -
NCT06579105
SOLSTICE: A Phase IIb, Randomized, Double-blind, Placebo-controlled and Open-label Active Comparator Study to Evaluate the Efficacy, Safety, and Tolerability of AZD5004 in Adults with Type 2 Diabetes Mellitus
This study is not currently enrolling.Research Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: The purpose of this study is to evaluate if the study medication AZD5004 can help improve glycemic control in persons with type 2 diabetes in conjunction with diet and exercise as...
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External Evaluation Plan: User Evaluation of the Next Generation CardioLab EP Recording System with the Prucka 3 Digital EP Amplifier
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Celebration, FloridaThe current CardioLab system is cleared by the FDA for use on patients of all ages when a physician determines that a patient would benefit from an electrophysiology procedure. CardioLab can be used...
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Evaluating the Efficacy of the Full Plate Living Program: A Cardiology Clinic-based Intervention in Winter Park, FL
This study is not currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Winter Park, FloridaThe primary objective of this study is to evaluate the impact of the Full Plate Living Program, developed by the Ardmore Institute of Health, on patient nutrition knowledge, diet, and lifestyle. The...
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NCT05858164
An open-label, phase 1, first-in-human, dose escalation and expansion study to evaluate the safety, tolerability, maximum tolerated or administered dose, pharmacokinetics, pharmacodynamics, and tumor response profile of the diacylglycerol kinase alpha inhibitor (DGKai) BAY 2862789 in participants with advanced solid tumors
This study is not currently enrolling.Associated Conditions: Metastatic Solid TumorsResearch Area: Clinical Cancer ResearchResearch Location: Celebration, FloridaThis study is being done to learn more about a new drug called BAY 2862789, an inhibitor of diacylglycerol kinase alpha (DGKα). BAY 2862789 is an immunotherapy drug that has been developed to activate...